The rootstock plays a fundamental role in adapting the vine to environmental conditions, ensuring the connection between the grape variety and the soil. The use of rootstocks has recently gained importance as the most effective and successful strategy for combating abiotic and biotic stresses in the world's leading wine-producing countries. However, selecting a specific rootstock is becoming increasingly challenging due to the availability of many new rootstocks. With all the potential benefits a rootstock can offer, the decision on which one to use is an important choice.