• The biological mechanisms that regulate body weight.
• The impact of the environment on the development of obesity.
• The method of diagnosis and the comorbidities of obesity.

Presents obesity as a complex disease, not merely as a result of lack of willpower. Explains why losing and maintaining weight is often difficult. Helps to dismantle the stigma surrounding obesity.

...you want to understand why obesity is a complex disease and which biological processes affect it. It is aimed at those interested in the scientific approach to the subject, written in a simple way.

«Obesity is a complex, multifactorial disease influenced by genetic, metabolic, environmental, and behavioral factors. Obesity is not merely the result of caloric imbalance, but reflects the complex interaction between biological mechanisms and the modern obesogenic environment. Every time we lose weight, the secretion of numerous hormones that regulate weight changes, while at the same time the calories we expend decrease.

Thus, our body opposes weight loss through many mechanisms, complicating every effort. The set point theory assumes that the human body has a genetically predetermined stable weight (set point or set range). Various physiological mechanisms maintain this set point stable and strongly resist any deviation.

This theory explains the high rate of weight regain (over 80%) after the cessation of any intervention (diet, exercise, medication, etc.).»

Dr. Youli Argyrakopoulou is a pathologist-diabetologist and director of the Diabetes and Obesity Clinic at the Athens Medical Center. She holds a master's degree and a doctorate in diabetes and obesity from the Medical School of EKPA, and she received further training at Barts and The London School of Medicine. She is an International Fellow of the World Obesity Federation (SCOPE) and a National Clinical Fellow of the European Association for the Study of Obesity (EASO). She actively participates in clinical studies and publications in reputable journals, as well as in conferences.