Contents

Preface to the 5th edition, vi

Preface to the 1st edition, vii

Preface to the Greek edition, viii

Legend for the symbols used in the images, ix

Summary of the immune system, x

Part 1

Immunity and the immune system

1. The nature of immunity, 3

2. Antigen recognition, 16

3. Development and activation of lymphocytes, 32

4. Interactions of lymphocytes, cytokines, and the lymphatic system, 43

5. Immunoglobulins, 58

6. Complement, 74

7. Phagocytes, 81

8. Mast cells, basophils, and eosinophils, 87

9. Killer cells, 95

Part 2

Immunopathology

10. Immunity and infection, 105

11. HIV and AIDS, 121

12. Congenital and acquired immunodeficiencies, 127

13. Inappropriate immune responses to endogenous and exogenous antigens, 147

14. Mechanisms of immunologic tissue damage, 162

15. Susceptibility to immunologic diseases, 174

16. Lymphoproliferative diseases, 182

17. Transplants, 196

18. Immunotherapy, 209

Index, 220